- Original Article
- Repetition of Apoptosis Induced by Amiloride Derivatives in Human Umbilical Vein Endothelial Cells
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Kyu Chang Park, Kyu Sang Park, Soo Jee Moon
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Clin Exp Pediatr. 2003;46(1):56-66. Published online January 15, 2003
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Purpose : Human umbilical vein endothelial cells(HUVECs) play an important role in regulating blood flow by releasing vasoactive substances. It has been reported that endothelial impairment and dysfunction might be a primary cause of placental vascular disease, which is manifested clinically as preeclampsia in mother and intrauterine growth restriction in fetus. Furthermore, the frequency of apoptotic changes is increased in... |
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- Treatment Outcomes in Children with High-Risk Acute Lymphoblastic Leukemia
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Kyu Chang Park, Ho Joon Im, Sang Yun Ahn, Hahng Lee
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Clin Exp Pediatr. 1999;42(3):383-389. Published online March 15, 1999
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Purpose : The survival rate of those with acute lymphoblastic leukemia(ALL) has been affected by several prognostic factors and previous reports show that a 4-year event-free survival(EFS) for high-risk(HR) group(Age≥10 years and/or WBC≥50,000/mm3 at diagnosis) was approximately 64%. We analyzed treatment outcomes and risk factors in HR-ALL.
Methods : Medical records of 27 patients with HR-ALL diagnosed between May, 1985 and... |
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